Detalhe da pesquisa
1.
Involvement of eNAMPT/TLR4 inflammatory signaling in progression of non-alcoholic fatty liver disease, steatohepatitis, and fibrosis.
FASEB J
; 37(3): e22825, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36809677
2.
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.
Am J Respir Cell Mol Biol
; 66(5): 497-509, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35167418
3.
Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.
Eur Respir J
; 57(5)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33243842
4.
Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α.
Am J Respir Cell Mol Biol
; 63(1): 92-103, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142369
5.
Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.
Am J Respir Crit Care Med
; 197(11): 1421-1432, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29425463
6.
The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.
Am J Respir Cell Mol Biol
; 51(5): 660-7, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821571
7.
An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction.
Biomed Pharmacother
; 170: 116103, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38160623
8.
TLR4 Ligation by eNAMPT, a Novel DAMP, is Essential to Sulfur Mustard- Induced Inflammatory Lung Injury and Fibrosis.
Eur J Respir Med
; 6(1): 389-397, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38390523
9.
Targeting SELPLG/P-selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter.
Pulm Circ
; 13(1): e12206, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36873461
10.
eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage.
J Transl Autoimmun
; 6: 100181, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36619655
11.
The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.
Front Physiol
; 14: 1129413, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37415908
12.
TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation.
Biochim Biophys Acta Mol Basis Dis
; 1868(12): 166562, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179995
13.
Critical role for the lung endothelial nonmuscle myosin light-chain kinase isoform in the severity of inflammatory murine lung injury.
Pulm Circ
; 12(2): e12061, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35514774
14.
Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization.
Transl Res
; 239: 44-57, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34139379
15.
eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.
Sci Rep
; 12(1): 696, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027578
16.
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.
Front Physiol
; 13: 916159, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35812318
17.
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.
Pulm Circ
; 11(4): 20458940211059712, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34790349